Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LIRAGLUTIDE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| BDNF | causes | gene | 0.70 |
| ATORVASTATIN | inhibits | drug | 0.70 |
| AMYLOID | causes | protein | 0.70 |
| CREB | activates | gene | 0.70 |
| CXCL10 | inhibits | gene | 0.65 |
| NRF2 | activates | gene | 0.65 |
| NRF2 | inhibits | gene | 0.65 |
| NRF2 | treats | gene | 0.65 |
| ROS | activates | phenotype | 0.65 |
| OXIDATIVE STRESS | inhibits | phenotype | 0.65 |
| OXIDATIVE STRESS | activates | phenotype | 0.65 |
| MAPK | regulates | gene | 0.65 |
| AMPK | targets | gene | 0.65 |
| NRF2 | associated_with | gene | 0.50 |
| BDNF | associated_with | gene | 0.50 |
| JNK | associated_with | gene | 0.50 |
| AUTOPHAGY | associated_with | phenotype | 0.50 |
| AMYLOID | associated_with | protein | 0.50 |
| ASTROCYTE | associated_with | cell_type | 0.50 |
| CREB | associated_with | gene | 0.50 |
| APP | associated_with | gene | 0.45 |
| GSK3B | associated_with | gene | 0.45 |
| AKT | associated_with | gene | 0.45 |
| CASP3 | associated_with | gene | 0.45 |
| BCL2 | associated_with | gene | 0.45 |
| BAX | associated_with | gene | 0.45 |
| CXCL10 | associated_with | gene | 0.45 |
| GJA1 | associated_with | gene | 0.45 |
| SEMAGLUTIDE | associated_with | drug | 0.45 |
| EXENATIDE | associated_with | drug | 0.45 |
| CORTEX | associated_with | brain_region | 0.45 |
| ALZHEIMER | associated_with | disease | 0.45 |
| ROS | associated_with | phenotype | 0.45 |
| METFORMIN | associated_with | drug | 0.45 |
| AMPK | associated_with | gene | 0.45 |
| APOPTOSIS | associated_with | phenotype | 0.45 |
| MAPK | associated_with | gene | 0.45 |
| SEMAGLUTIDE | metabolizes | drug | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| BDNF | regulates | gene | 0.70 |
| ALZHEIMER'S DISEASE | produces | disease | 0.60 |
| CEREBRAL CORTEX | associated_with | brain_region | 0.45 |
| ALZHEIMER'S DISEASE | associated_with | disease | 0.45 |
| NEURODEGENERATION | associated_with | disease | 0.45 |
| MITOCHONDRIAL DYSFUNCTION | associated_with | phenotype | 0.45 |
| INSULIN SIGNALING | associated_with | pathway | 0.45 |
| NEUROINFLAMMATION | associated_with | phenotype | 0.45 |
| OXIDATIVE STRESS | associated_with | phenotype | 0.45 |
| INFLAMMATION | associated_with | phenotype | 0.45 |
| PARKINSON'S DISEASE | associated_with | disease | 0.45 |
| AMPK PATHWAY | associated_with | pathway | 0.45 |
| APP | inhibits | gene | 0.35 |
| CEREBRAL CORTEX | inhibits | brain_region | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||