ROBO1

Understanding Entity Pages

This page aggregates everything SciDEX knows about ROBO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ROBO1 (Roundabout Guidance Receptor 1) is a transmembrane receptor for Slit ligands, critical for axon guidance, neuronal migration, and implicated in neurodegenerative diseases.

View on Wiki →

graph TD
    ROBO1["<b>ROBO1</b>"]
    Als{"Als"}
    ROBO1 -->|"associated with"| Als
    Cardiac{"Cardiac"}
    ROBO1 -->|"associated with"| Cardiac
    UBIQUITIN["UBIQUITIN"]
    ROBO1 -->|"activates"| UBIQUITIN
    GAD2["GAD2"]
    ROBO1 -->|"associated with"| GAD2
    PIK3CB["PIK3CB"]
    ROBO1 -->|"associated with"| PIK3CB
    NOS1["NOS1"]
    ROBO1 -->|"associated with"| NOS1
    CFTR["CFTR"]
    ROBO1 -->|"associated with"| CFTR
    EPHB4["EPHB4"]
    ROBO1 -->|"associated with"| EPHB4
    MMP2["MMP2"]
    ROBO1 -->|"associated with"| MMP2
    HIP1R["HIP1R"]
    ROBO1 -->|"associated with"| HIP1R
    neurodegeneration["neurodegeneration"]
    ROBO1 -->|"implicated in"| neurodegeneration
    RYR2["RYR2"]
    RYR2 -->|"associated with"| ROBO1
    SCN1A["SCN1A"]
    SCN1A -->|"associated with"| ROBO1
    style ROBO1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0