CFTR

Understanding Entity Pages

This page aggregates everything SciDEX knows about CFTR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CFTR is a gene implicated in neurodegeneration research. Key relationships include: interacts with, associated with, regulates. Associated with ALS, Als, Asthma. Connected to 312 entities in the SciDEX knowledge graph.

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graph TD
    CFTR["CFTR"] -->|"Interacts With"| Cancer["Cancer"]
    CFTR["CFTR"] -->|"Interacts With"| Als["Als"]
    CFTR["CFTR"] -->|"Interacts With"| Ms["Ms"]
    CFTR["CFTR"] -->|"Regulates"| Fibrosis["Fibrosis"]
    CFTR["CFTR"] -->|"Interacts With"| SQSTM1["SQSTM1"]
    CFTR["CFTR"] -->|"Interacts With"| RPS6KB1["RPS6KB1"]
    CFTR["CFTR"] -->|"Interacts With"| GRB2["GRB2"]
    CFTR["CFTR"] -->|"Interacts With"| RHEB["RHEB"]
    OPTN["OPTN"] -->|"Interacts With"| CFTR["CFTR"]
    CASP3["CASP3"] -->|"Regulates"| CFTR["CFTR"]
    AKT1["AKT1"] -->|"Regulates"| CFTR["CFTR"]
    CALCOCO2["CALCOCO2"] -->|"Regulates"| CFTR["CFTR"]
    CGAS["CGAS"] -->|"Regulates"| CFTR["CFTR"]
    style CFTR fill:#8d4900,color:#e0e0e0
    style Cancer fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Ms fill:#b71c1c,color:#e0e0e0
    style Fibrosis fill:#b71c1c,color:#e0e0e0
    style SQSTM1 fill:#8d4900,color:#e0e0e0
    style RPS6KB1 fill:#8d4900,color:#e0e0e0
    style GRB2 fill:#8d4900,color:#e0e0e0
    style RHEB fill:#8d4900,color:#e0e0e0
    style OPTN fill:#8d4900,color:#e0e0e0
    style CASP3 fill:#8d4900,color:#e0e0e0
    style AKT1 fill:#8d4900,color:#e0e0e0
    style CALCOCO2 fill:#8d4900,color:#e0e0e0
    style CGAS fill:#8d4900,color:#e0e0e0