STX3

Understanding Entity Pages

This page aggregates everything SciDEX knows about STX3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Syntaxin 3 gene encoding a SNARE protein critical for synaptic vesicle exocytosis and membrane fusion in neurons - implicated in Alzheimer's, Parkinson's, and neurodevelopmental disorders

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flowchart TD
    N0["STX3"]
    N1["Alzheimer"]
    N0 -->|"regulates"| N1
    N2["Neurodegeneration"]
    N0 -->|"regulates"| N2
    N3["Cancer"]
    N0 -->|"regulates"| N3
    N4["Als"]
    N0 -->|"regulates"| N4
    N5["Neuroinflammation"]
    N0 -->|"regulates"| N5
    N6["FKBP5"]
    N0 -->|"regulates"| N6
    N7["SEC22B"]
    N0 -->|"regulates"| N7
    N8["SNAP23"]
    N0 -->|"regulates"| N8
    N9["Autophagy"]
    N0 -->|"regulates"| N9
    N10["Microglia"]
    N0 -->|"regulates"| N10
    N11["HSP90"]
    N11 -->|"regulates"| N0
    N12["ALZHEIMER"]
    N12 -->|"regulates"| N0
    N13["SNAP29"]
    N13 -->|"regulates"| N0
    N14["MICROGLIA"]
    N14 -->|"regulates"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N4 disease
    class N5 disease
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 pathway
    class N11 gene
    class N12 gene
    class N13 gene
    class N14 gene