gene

SNAP23

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNAP23: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

54Connections
0Hypotheses
0Analyses
31Outgoing
23Incoming

Summary

SNAP23 is a gene implicated in neurodegeneration research. Key relationships include: activates, implicated in. Associated with Alzheimer, Ms. Connected to 13 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolSNAP23
Chromosome15q21.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionall neurons
Molecular Weight23 kDa
Exons6
PathwaysAutophagy
Ensembl IDENSG00000100939
GeneCardsSNAP23
Human Protein AtlasSNAP23
N-terminal prefixRegulatory function
SNARE motif (x3)Core coiled-coil domain
C-terminal transmembraneMembrane anchoring
Associated Diseasesneurodegeneration
InteractionsAPP, TAU, ZBP1, BAX, HERC5, STX4
KG Connections54 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (13)

Knowledge base pages for this entity

Canonical Page

SNAP23 Gene

gene · 629 words

Exosome Biogenesis in Neurodegeneration

mechanism · 3104 words

VAMP8 — Vesicle Associated Membrane Protein 8

gene · 2502 words

SEC22B Gene

gene · 1791 words

SNAP47 Gene — Synaptosome-Associated Protein 47

gene · 1498 words

STX11 Gene

gene · 1222 words

Pathway Diagram

graph TD
    SNAP23["<b>SNAP23</b>"]
    Alzheimer{"Alzheimer"}
    SNAP23 -->|"activates"| Alzheimer
    Ms{"Ms"}
    SNAP23 -->|"activates"| Ms
    Autophagy(["Autophagy"])
    SNAP23 -->|"activates"| Autophagy
    APP["APP"]
    SNAP23 -->|"activates"| APP
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    SNAP23 -->|"activates"| NEURODEGENERATIVE_DISEASES
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    SNAP23 -->|"activates"| ALZHEIMER_S_DISEASE
    APP_PS1["APP/PS1"]
    SNAP23 -->|"activates"| APP_PS1
    TAU["TAU"]
    SNAP23 -->|"activates"| TAU
    AUTOPHAGY["AUTOPHAGY"]
    SNAP23 -->|"activates"| AUTOPHAGY
    NEUROTOXICITY["NEUROTOXICITY"]
    SNAP23 -->|"activates"| NEUROTOXICITY
    neurodegeneration["neurodegeneration"]
    SNAP23 -->|"implicated in"| neurodegeneration
    APP -->|"activates"| SNAP23
    APP_PS1 -->|"activates"| SNAP23
    style SNAP23 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (31)

TargetRelationTypeStr
Alzheimeractivatesdisease0.65
Msactivatesdisease0.65
Alzheimerregulatesdisease0.65
Neurodegenerationregulatesdisease0.65
Cancerregulatesdisease0.65

Incoming (23)

SourceRelationTypeStr
APPactivatesgene0.60
TAUactivatesgene0.60
HSP90regulatesgene0.60
SNAP29regulatesgene0.60
STX4regulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found