concept

SYN2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYN2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

31Outgoing

15Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	SYN2A
Key Genes/Proteins	ACHE, GAP43, OXIDATIVE STRESS, MANF, ROS, AXON
Related Diseases	ALS, Inflammation, Als

Wiki Pages (1)

Knowledge base pages for this entity

SYN2 Gene

gene · 640 words

→

Pathway Diagram

graph TD
    SYN2A["SYN2A"]
    SYN2A -->|"activates"| ALS["ALS"]
    SYN2A -->|"activates"| Inflammation["Inflammation"]
    SYN2A -->|"activates"| Als["Als"]
    SYN2A -->|"activates"| ACHE["ACHE"]
    SYN2A -->|"inhibits"| GAP43["GAP43"]
    SYN2A -->|"activates"| OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    SYN2A -->|"inhibits"| MANF["MANF"]
    SYN2A -->|"activates"| ROS["ROS"]
    Bpmc["Bpmc"] -->|"downregulates"| SYN2A
    TUBULIN["TUBULIN"] -->|"inhibits"| SYN2A
    ACHE -->|"activates"| SYN2A
    MYELIN["MYELIN"] -->|"activates"| SYN2A
    ROS -->|"activates"| SYN2A
    BPMC["BPMC"] -->|"inhibits"| SYN2A
    APOPTOSIS["APOPTOSIS"] -->|"activates"| SYN2A
    MBP["MBP"] -->|"inhibits"| SYN2A

Outgoing (31)

Target	Relation	Type	Str
ALS	activates	disease	0.65
Inflammation	activates	disease	0.65
Als	activates	disease	0.65
ACHE	activates	gene	0.60
GAP43	inhibits	gene	0.60
OXIDATIVE STRESS	activates	gene	0.60
MANF	inhibits	gene	0.60
ROS	activates	gene	0.60
AXON	activates	gene	0.60
NEURON	activates	gene	0.60
INFLAMMATION	activates	gene	0.60
NEUROTOXICITY	activates	gene	0.60
MBP	inhibits	gene	0.60
ELAVL3	inhibits	gene	0.60
AND	inhibits	gene	0.60
APOPTOSIS	activates	gene	0.60
GENES	inhibits	gene	0.60
BPMC	inhibits	gene	0.60
GFAP	inhibits	gene	0.60
MYELIN	activates	gene	0.60
Oxidative Stress	activates	pathway	0.60
Apoptosis	activates	pathway	0.60
Neuron	activates	cell_type	0.60
TUBULIN	inhibits	gene	0.60
Neutrophil	activates	cell_type	0.60
Caspase	activates	protein	0.60
Tubulin	inhibits	protein	0.60
Raf	activates	protein	0.60
Rb	activates	protein	0.60
Spinal Cord	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55

Incoming (15)

Source	Relation	Type	Str
Bpmc	downregulates	compound	0.85
TUBULIN	inhibits	gene	0.60
ACHE	activates	gene	0.60
MYELIN	activates	gene	0.60
ROS	activates	gene	0.60
BPMC	inhibits	gene	0.60
APOPTOSIS	activates	gene	0.60
MBP	inhibits	gene	0.60
GAP43	inhibits	gene	0.60
NEURON	activates	gene	0.60
MANF	inhibits	gene	0.60
AXON	activates	gene	0.60
OXIDATIVE STRESS	activates	gene	0.60
GFAP	inhibits	gene	0.60
ELAVL3	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found