ELAVL3

Understanding Entity Pages

This page aggregates everything SciDEX knows about ELAVL3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ELAVL3 is a gene implicated in neurodegeneration research. Key relationships include: activates, inhibits, regulates. Associated with ALS, Als, Inflammation. Connected to 46 entities in the SciDEX knowledge graph.

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graph TD
    ELAVL3["<b>ELAVL3</b>"]
    TREM2["TREM2"]
    ELAVL3 -->|"upregulates"| TREM2
    neurodegeneration["neurodegeneration"]
    ELAVL3 -->|"associated with"| neurodegeneration
    Als{"Als"}
    ELAVL3 -->|"activates"| Als
    Ms{"Ms"}
    ELAVL3 -->|"activates"| Ms
    Inflammation{"Inflammation"}
    ELAVL3 -->|"activates"| Inflammation
    ALS{"ALS"}
    ELAVL3 -->|"activates"| ALS
    MANF["MANF"]
    ELAVL3 -->|"inhibits"| MANF
    MBP["MBP"]
    ELAVL3 -->|"inhibits"| MBP
    Oxidative_Stress(["Oxidative Stress"])
    ELAVL3 -->|"activates"| Oxidative_Stress
    Apoptosis(["Apoptosis"])
    ELAVL3 -->|"activates"| Apoptosis
    GFAP["GFAP"]
    ELAVL3 -->|"inhibits"| GFAP
    GAP43["GAP43"]
    ELAVL3 -->|"inhibits"| GAP43
    GFAP -->|"inhibits"| ELAVL3
    GAP43 -->|"inhibits"| ELAVL3
    MBP -->|"inhibits"| ELAVL3
    GENES["GENES"]
    GENES -->|"inhibits"| ELAVL3
    MANF -->|"inhibits"| ELAVL3
    ACHE["ACHE"]
    ACHE -->|"activates"| ELAVL3
    ROS["ROS"]
    ROS -->|"activates"| ELAVL3
    AXON["AXON"]
    AXON -->|"activates"| ELAVL3
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| ELAVL3
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    OXIDATIVE_STRESS -->|"activates"| ELAVL3
    TUBULIN["TUBULIN"]
    TUBULIN -->|"inhibits"| ELAVL3
    NEURON["NEURON"]
    NEURON -->|"activates"| ELAVL3
    style ELAVL3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0