UBE3A

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBE3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

UBE3A is a gene implicated in neurodegeneration research. Key relationships include: regulates, contributes to, implicated in. Associated with Inflammation, Ms, Neuroinflammation. Connected to 23 entities in the SciDEX knowledge graph.

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graph TD
    UBE3A["<b>UBE3A</b>"]
    Parkinson{"Parkinson"}
    UBE3A -->|"regulates"| Parkinson
    Ms{"Ms"}
    UBE3A -->|"regulates"| Ms
    Neuroinflammation{"Neuroinflammation"}
    UBE3A -->|"regulates"| Neuroinflammation
    Inflammation{"Inflammation"}
    UBE3A -->|"regulates"| Inflammation
    CREB3["CREB3"]
    UBE3A -->|"contributes to"| CREB3
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"]
    UBE3A -->|"regulates"| ALPHA_SYNUCLEIN
    PARKIN["PARKIN"]
    UBE3A -->|"regulates"| PARKIN
    UBIQUITIN["UBIQUITIN"]
    UBE3A -->|"regulates"| UBIQUITIN
    PARK6["PARK6"]
    UBE3A -->|"regulates"| PARK6
    MITOPHAGY["MITOPHAGY"]
    UBE3A -->|"regulates"| MITOPHAGY
    MAPK8["MAPK8"]
    UBE3A -->|"contributes to"| MAPK8
    ASTROCYTES["ASTROCYTES"]
    UBE3A -->|"regulates"| ASTROCYTES
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"regulates"| UBE3A
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"regulates"| UBE3A
    style UBE3A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0