CREB3

Understanding Entity Pages

This page aggregates everything SciDEX knows about CREB3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CREB3 is a gene implicated in neurodegeneration research. Key relationships include: regulates, contributes to, associated with. Associated with Aging, Als, Cardiovascular. Connected to 39 entities in the SciDEX knowledge graph.

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graph TD
    CREB3["<b>CREB3</b>"]
    Parkinson{"Parkinson"}
    CREB3 -->|"regulates"| Parkinson
    Ms{"Ms"}
    CREB3 -->|"regulates"| Ms
    Neuroinflammation{"Neuroinflammation"}
    CREB3 -->|"regulates"| Neuroinflammation
    Inflammation{"Inflammation"}
    CREB3 -->|"regulates"| Inflammation
    Als{"Als"}
    CREB3 -->|"associated with"| Als
    Aging{"Aging"}
    CREB3 -->|"associated with"| Aging
    CREB3 -->|"associated with"| Ms
    Cardiovascular{"Cardiovascular"}
    CREB3 -->|"associated with"| Cardiovascular
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"]
    CREB3 -->|"regulates"| ALPHA_SYNUCLEIN
    PARKIN["PARKIN"]
    CREB3 -->|"regulates"| PARKIN
    UBIQUITIN["UBIQUITIN"]
    CREB3 -->|"regulates"| UBIQUITIN
    PARK6["PARK6"]
    CREB3 -->|"regulates"| PARK6
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"regulates"| CREB3
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"regulates"| CREB3
    UBE3A["UBE3A"]
    UBE3A -->|"contributes to"| CREB3
    AGING["AGING"]
    AGING -->|"associated with"| CREB3
    TSC1["TSC1"]
    TSC1 -->|"contributes to"| CREB3
    style CREB3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0