concept

PAEONIFLORIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PAEONIFLORIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

39Connections

0Hypotheses

0Analyses

37Outgoing

2Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	PAEONIFLORIN

Wiki Pages (6)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    PAEONIFLORIN["PAEONIFLORIN"]
    PAEONIFLORIN -.protects against.-> Drug_Induced_Liver_Injury["Drug-Induced Liver Injury"]
    PAEONIFLORIN -.protects against.-> APAP_induced_Hepatic_Damage["APAP-induced Hepatic Damage"]
    PAEONIFLORIN -->|"treats"| Acetaminophen_Induced_Hepatic_["Acetaminophen-Induced Hepatic Damage"]
    PAEONIFLORIN -->|"activates"| Autophagy["Autophagy"]
    PAEONIFLORIN -->|"modulates"| MAPK_Signaling["MAPK Signaling"]
    PAEONIFLORIN -->|"inhibits"| MAPK["MAPK"]
    PAEONIFLORIN -->|"inhibits"| mTOR["mTOR"]
    PAEONIFLORIN -->|"contributes to"| LC3["LC3"]

Outgoing (37)

Target	Relation	Type	Str
Drug-Induced Liver Injury	protects_against	disease	0.95
APAP-induced Hepatic Damage	protects_against	disease	0.95
HSF1	upregulates	gene	0.95
NRF1	upregulates	gene	0.95
PIEZO1	binds	gene	0.95
Acetaminophen-Induced Hepatic Damage	treats	disease	0.93
PIEZO1	therapeutic_target	gene	0.93
Renal Fibrosis	treats	disease	0.92
Endothelial-Mesenchymal Transition	suppresses	process	0.92
Autophagy	activates	process	0.92
MAPK Signaling	modulates	pathway	0.91
LC3	contributes_to	protein	0.90
ATG5	contributes_to	protein	0.90
ATG7	contributes_to	protein	0.90
BECN1	contributes_to	protein	0.90
mTOR Signaling	downregulates	pathway	0.90
TNF	downregulates	gene	0.90
BDNF	upregulates	gene	0.90
Th17/Treg balance	regulates	process	0.90
Microvascular Rarefaction	protects_against	phenotype	0.90
MAPK	inhibits	protein	0.90
mTOR	inhibits	protein	0.90
Apoptosis	inhibits	process	0.90
P38	targets	protein	0.88
MTOR	downregulates	gene	0.88
Hepatocyte Apoptosis	inhibits	process	0.88
CDH5	upregulates	gene	0.88
NOS3	upregulates	gene	0.88
ATG5	upregulates	gene	0.87
Extracellular Matrix Deposition	suppresses	process	0.87
p38	targets	protein	0.85
LC3	upregulates	protein	0.85
Rorγt	binds	protein	0.85
FOXP3	binds	gene	0.85
Reactive Oxygen Species	modulates	process	0.85
Parkinson'S Disease	protects_against	disease	0.85
MITOCHONDRIA	modulates	cell_type	0.80

Incoming (2)

Source	Relation	Type	Str
RORC	interacts_with	gene	0.85
FOXP3	interacts_with	gene	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

PAEONIFLORIN

Understanding Entity Pages

Wiki Pages (6)

ATG7 Protein — Autophagy-Related Protein 7

LC3 (Microtubule-Associated Protein 1 Light Chain 3)

LC3 Protein

ATG5 Protein

BECN1 Gene