NRF1

Understanding Entity Pages

This page aggregates everything SciDEX knows about NRF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NRF1 is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, inhibits. Associated with ALS, Aging, Als. Connected to 251 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    NRF1["NRF1"]
    NRF1 -->|"activates"| PINK1["PINK1"]
    NRF1 -->|"activates"| PRKN["PRKN"]
    NRF1 -->|"activates"| Als["Als"]
    NRF1 -->|"activates"| Neurodegeneration["Neurodegeneration"]
    NRF1 -->|"activates"| Ms["Ms"]
    NRF1 -->|"regulates"| Alzheimer["Alzheimer"]
    NRF1 -->|"regulates"| Cancer["Cancer"]
    NRF1 -->|"regulates"| Stroke["Stroke"]
    NRF1 -->|"activates"| Fibrosis["Fibrosis"]
    PGC1A["PGC1A"] -->|"activates"| NRF1
    PPARGC1A["PPARGC1A"] -->|"activates"| NRF1
    TFAM["TFAM"] -->|"activates"| NRF1
    MFN1["MFN1"] -->|"activates"| NRF1
    DNM1L["DNM1L"] -->|"target for"| NRF1
    DRP1["DRP1"] -->|"activates"| NRF1
    JUN["JUN"] -->|"target for"| NRF1
    GENES["GENES"] -->|"target for"| NRF1
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"] -->|"activates"| NRF1
    AMPK["AMPK"] -->|"regulates"| NRF1