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RHOT1

RHOT1 Protein

Score: 0.464 Price: $0.43 Low Druggability Status: active
HYPOTHESES
1
PAPERS
8
KG EDGES
0
DEBATES
0

3D Protein Structure

🧬 RHOT1 — PDB 4I5R Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability
Low
Score: 0.50
Clinical Stage
Phase I
Target Class
Protein
Safety
0.50
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.50
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
Known Drugs:
No known drugs targeting this protein
Structural Data:

🧬 3D Protein Structure

🧬 RHOT1 — PDB 4I5R Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (1)

Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy0.426

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.50 (20%) Evidence 0.64 (20%) Safety 0.50 (15%) Competitive 0.90 (10%) Connectivity 0.00 (10%) 0.464 composite

Knowledge Graph (20)

associated with (1)

RHOT1 → MIRO1

interacts with (19)

RHOT1 → BNIP3L
RHOT1 → NDP52
RHOT1 → HIF1A
RHOT1 → MAP1LC3B
RHOT1 → GBA
...and 14 more

Debate History (0)

No debates yet

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