gene 3,036 words KG: HTT
Contents

HTT (Huntingtin)

🧬 Gene Info
Gene SymbolHTT
Full NameHuntingtin
Chromosome4p16.3.
Functionis a large, multifunctional protein encoded by the HTT gene on chromosome 4p16.
Subcellular Localizationand protein interactions
Molecular Weight350 kDa
Amino Acids144 aa
Exons67
PathwaysAutophagy, Dna Repair
UniProt IDP42857
NCBI Gene ID3064
Ensembl IDENSG00000197393
OMIM143100
GeneCardsHTT
Human Protein AtlasHTT
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/Compoundsdimethyl fumarate, rapamycin, RAPAMYCIN
InteractionsABP, ACHE, Actin, AD, AKT, ALS
SciDEX HypothesesGlial Progenitor Cell Support in Huntington's Dise
KG Connections799 knowledge graph edges
DatabasesGeneCardsHPASTRING

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