| Gene Symbol | CDK5 |
| Full Name | Cyclin-Dependent Kinase 5 |
| Chromosome | 7q36.1 |
| Protein Family | CMGC kinase group, CDK family |
| Protein Type | Serine/Threonine Kinase |
| Function | Cdk5 knockout mice die at birth with severe cortical layering defects due to failed neuronal migration. |
| Primary Expression | Cytoplasm, nucleus, synapses, growth cones, perinuclear region |
| Amino Acids | 291 aa |
| Pathways | Apoptosis, Autophagy, Checkpoint Inhibitor, Immune Checkpoint, Immune Response |
| UniProt ID | Q00535 |
| NCBI Gene ID | 1020 |
| Ensembl ID | ENSG00000164885 |
| OMIM | 123831 |
| GeneCards | CDK5 |
| Human Protein Atlas | CDK5 |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer's disease, Ataxia |
| Known Drugs/Compounds | RESVERATROL, metformin, METFORMIN, N-ACETYLCYSTEINE, Protopanaxatriol |
| Interactions | LIS1, DAB1, PAFAH1B1, DRP1, MAPT, HSP90AA1 |
| KG Connections | 612 knowledge graph edges |
| Databases | GeneCardsHPASTRING |