| Gene Symbol | DAPK1 |
| Full Name | Death-Associated Protein Kinase 1 |
| Chromosome | 9p21.3 |
| Protein Family | CaMK (Calcium/Calmodulin-dependent protein kinase) family |
| Protein Type | Serine/Threonine Kinase |
| Function | encodes a calcium/calmodulin-dependent serine/threonine kinase that functions as a positive regulator of apoptosis, autophagy, and programmed cell death. |
| Primary Expression | the brain, particularly in neurons, where it integrates calcium signaling with cell death pathways |
| Subcellular Localization | and interactions |
| Molecular Weight | 160 kDa |
| Amino Acids | 1056 aa |
| Pathways | PI3K |
| UniProt ID | P53355 |
| NCBI Gene ID | 1612 |
| Ensembl ID | ENSG00000196730 |
| OMIM | 600730 |
| GeneCards | DAPK1 |
| Human Protein Atlas | DAPK1 |
| Associated Diseases | AD, ALS, AMI, Alzheimer, Alzheimer's disease |
| Interactions | HSPG2, IL1B, APP, EIF2AK2, HMGCR, PARP1 |
| SciDEX Hypotheses | DAPK1 Inhibition as Dual-Mechanism Neuroprotection |
| KG Connections | 191 knowledge graph edges |
| Databases | GeneCardsHPASTRING |