gene 673 words KG: EIF2S1
Contents

EIF2S1 (eIF2α)

🧬 Gene Info
Gene SymbolEIF2S1
FunctionThe eIF2·GTP·Met-tRNAi ternary complex is essential for every round of translation initiation.
PathwaysAutophagy, Er Stress, Unfolded Protein Response
Ensembl IDENSG00000134001
GeneCardsEIF2S1
Human Protein AtlasEIF2S1
Associated DiseasesAD, ALI, Als, Cardiovascular, Ischemia, Ms
InteractionsABCD3, ALS, ALZHEIMER, ALZHEIMER DISEASE, AMBRA1, AMPK
KG Connections466 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
RNA Granule Nucleation Site Modulation
Score: 0.66
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (3)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

ATP P2X3 Receptor Neurons
cell · KG edge: interacts_with
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: associated_with
ABCD3 Gene
gene · KG edge: interacts_with
AMBRA1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CAT interacts_with EIF2S1
OPTN interacts_with EIF2S1
DNM1L interacts_with EIF2S1
CANX interacts_with EIF2S1
LGALS3 interacts_with EIF2S1
CALCOCO2 interacts_with EIF2S1
G3BP1 interacts_with EIF2S1
PEX3 interacts_with EIF2S1
SQSTM1 interacts_with EIF2S1
BCL2 interacts_with EIF2S1

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