gene 2,642 words KG: LARS2
Contents

LARS2 — Leucyl-tRNA Synthetase 2, Mitochondrial

🧬 Gene Info
Gene SymbolLARS2
Full NameLeucyl-tRNA Synthetase 2, Mitochondrial
Chromosome3p21.31
Protein TypeSynthetase
Functionencodes a mitochondrial aminoacyl-tRNA synthetase that catalyzes the attachment of leucine to mitochondrial tRNA molecules.
PathwaysDifferentiation, Mitochondrial Function
UniProt IDQ9H3K1
NCBI Gene ID57505
Ensembl IDENSG00000090339
OMIM615912
GeneCardsLARS2
Human Protein AtlasLARS2
Associated DiseasesAtaxia, Cognitive Impairment, Ms
InteractionsAND, ATP, DRP1, MFN1, MFN2, OPA1
KG Connections42 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (29)

Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Arginine Methylation Enhancement Therapy
Score: 0.65
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
← Prevpg 2/2

Related Analyses (11)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (14)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
ATM Gene
gene · KG edge: associated_with
CLPP (Caseinolytic Mitochondrial Matrix Peptidase Prote
gene · KG edge: associated_with
DRP1 Gene - Dynamin 1-Like Protein
gene · KG edge: inhibits
FMR1 — Fragile X Messenger Ribonucleoprotein 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

DRP1 inhibits LARS2
MFN1 inhibits LARS2
OPA1 inhibits LARS2
LARS2 inhibits MFN2
LARS2 activates PIEZO1
WFS1 associated_with LARS2
HARS associated_with LARS2
ATM associated_with LARS2
CLPP associated_with LARS2
SETX associated_with LARS2

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