gene 2,077 words KG: PCBP1
Contents

PCBP1 Gene

🧬 Gene Info
Gene SymbolPCBP1
Full NamePoly(rC) Binding Protein 1
AliasesPoly(rC)-Binding Protein 1
Chromosome2p13.3.
Functionencodes a critical RNA-binding protein involved in post-transcriptional gene regulation.
Molecular Weight38 kDa
Amino Acids371 aa
PathwaysAkt, Pi3K
UniProt IDQ15365
NCBI Gene ID5099
Ensembl IDENSG00000131469
OMIM604213
GeneCardsPCBP1
Human Protein AtlasPCBP1
Associated DiseasesMs, Tumor
InteractionsAPOPTOSIS, ASC, ATG7, AUTOPHAGY, CANCER, COX2
KG Connections67 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Extracellular Matrix Stiffness Modulation
Score: 0.69
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Apoptosis in Neurodegeneration
entity · KG edge: inhibits
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
ASC (PYCARD)
gene · KG edge: expressed_in
ATG7 Gene
gene · KG edge: activates
GPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

PCBP1 regulates PI3K
PCBP1 regulates AKT
HSP90AA1 activates PCBP1
ATG7 activates PCBP1
PCBP1 binds FERRITINH
PCBP1 regulates FERRITINH
PCBP1 regulates TNF
PCBP1 regulates IL1B
PCBP1 regulates IL6
PI3K regulates PCBP1

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