| Gene Symbol | SPI1 |
| Full Name | PU.1 Transcription Factor / Spi-1 Proto-Oncogene |
| Aliases | SPI1/PU.1 |
| Chromosome | 19q13.3 |
| Protein Type | Transcription Factor |
| Function | encodes a transcription factor of the E26 transformation-specific (ETS) family. |
| Amino Acids | 270 aa |
| Pathways | Amyloid, Mtor, Pi3K/Akt |
| UniProt ID | P17947 |
| NCBI Gene ID | 6678 |
| Ensembl ID | ENSG00000135336 |
| OMIM | 165010 |
| GeneCards | SPI1 |
| Human Protein Atlas | SPI1 |
| Associated Diseases | AD, ALI, Als, Alzheimer, Alzheimer's disease |
| Interactions | Actin, AKT, ALZHEIMER, ALZHEIMER DISEASE, ALZHEIMER'S DISEASE, AMYLOID |
| SciDEX Hypotheses | Neurovascular Unit SPI1 Signaling Hub Temporal SPI1 Inhibition for Neuroplasticity Recov SPI1-Mediated Metabolic Reprogramming in Neuroinfl (+3 more) |
| KG Connections | 434 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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