gene 1,654 words KG: VCAM1
Contents

VCAM1 - Vascular Cell Adhesion Molecule 1

🧬 Gene Info
Gene SymbolVCAM1
Full NameVascular Cell Adhesion Molecule 1
AliasesCD106
Chromosome1p21.2
FunctionCell adhesion molecule mediating leukocyte endothelial attachment
Molecular Weight81.3 kDa
Amino Acids739
PathwaysLeukocyte extravasation, NF-kB signaling
UniProt IDP19320
NCBI Gene ID7412
Ensembl IDENSG00000162692
GeneCardsVCAM1
Human Protein AtlasVCAM1
Official NameVascular Cell Adhesion Molecule 1
NCBI ReferenceNM_001078
Associated DiseasesAls, Alzheimer, Inflammation, Multiple Sclerosis, dementia
InteractionsLDLR, TNF, NOX4, SOD2, NRF2, CXCL1
KG Connections177 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
APOE Isoform Expression Across Glial Subtypes
Score: 0.48

Related Analyses (3)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
Dementia Australia
institution · KG edge: expressed_in
Alzheimer Indonesia
institution · KG edge: expressed_in
ENO1 Gene
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

VCAM1 associated_with ICAM1
VCAM1 inhibits LDLR
VCAM1 inhibits TNF
VCAM1 biomarker_for LMNA
VCAM1 biomarker_for GAPDH
VCAM1 activates NOX4
VCAM1 activates SOD2
VCAM1 activates NRF2
VCAM1 regulates AKT
VCAM1 regulates APOE