| Gene Symbol | HMGB1 |
| Full Name | High Mobility Group Box 1 |
| Chromosome | 13q12.3 |
| Function | is a gene on chromosome 13q12. |
| Primary Expression | Ubiquitous; enriched in neurons, microglia, astrocytes |
| Molecular Weight | 25 kDa |
| Amino Acids | 215 aa |
| Exons | 5 |
| Pathways | Adaptive Immunity, Akt, Autophagy Machinery, Ferroptosis, Mapk |
| UniProt ID | P09429 |
| NCBI Gene ID | 3146 |
| Ensembl ID | ENSG00000189403 |
| OMIM | 163905 |
| GeneCards | HMGB1 |
| Human Protein Atlas | HMGB1 |
| Associated Diseases | Aging, Als, Alzheimer, Anxiety-like behavior, cancer |
| Known Drugs/Compounds | Box-A, curcumin, Glycyrrhizic Acid, Omega-3 Polyunsaturated Fatty Acids, rapamycin, RAPAMYCIN |
| Interactions | ABCA1, ABCG1, ACHE, Actin, AD, Adiponectin |
| KG Connections | 1382 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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