mechanism 2,324 words KG: GBA
Contents

gaucher-disease-pathway

Mechanism Info
NameGBA
Key Genes/ProteinsALZHEIMER'S DISEASE
Related DiseasesLewy body pathology, Parkinson Disease, Gaucher Disease, Gaucher's disease, Parkinson's Disease
Related Pathwaysautophagy

Knowledge Graph

Related Hypotheses (16)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain A
Score: 0.51
Noradrenergic-Tau Propagation Blockade
Score: 0.51
Autophagosome Maturation Checkpoint Control
Score: 0.49

Related Analyses (30)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

GBA interacts_with FUNDC1
GBA interacts_with AMBRA1
GBA interacts_with PINK1
GBA interacts_with BCL2L13
GBA interacts_with NLRP3
GBA interacts_with ABCD3
GBA interacts_with FIP200
GBA interacts_with RTN3
GBA interacts_with SESN2
GBA associated_with PLIN2