gene 2,871 words KG: TERT
Contents

TERT Gene

🧬 Gene Info
Gene SymbolTERT
Full NameTelomerase Reverse Transcriptase
Chromosome5p15.33
Functiondyskerin (DKC1): Stabilizes the complex
Primary Expressionhippocampal subgranular zone (SGZ)
Molecular Weight127 kDa
Amino Acids1132 aa
Exons16
PathwaysTelomere Dysfunction
UniProt ID[O14748](https://www.uniprot.org/uniprot/O14748)
Ensembl IDENSG00000164362
OMIM607409
GeneCardsTERT
Human Protein AtlasTERT
Reverse transcriptase activityCatalyzes addition of TTAGGG repeats to telomeres
Associated DiseasesAD, ALI, Als, AMI, cancer
Known Drugs/CompoundsTAC
InteractionsACVR2A, AGING, AKT, AKT3, AMPK, AND
KG Connections525 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

IDH1 therapeutic_target TERT
VEGFA therapeutic_target TERT
MDM4 therapeutic_target TERT
APOB therapeutic_target TERT
SF3B1 therapeutic_target TERT
MET therapeutic_target TERT
SMARCA4 therapeutic_target TERT
TERT therapeutic_target JUN
TERT therapeutic_target EEF1A1
TERT therapeutic_target MCL1

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