Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 3,107 pages

🔬 NTF4 ProteinKG

protein · 5,111 words · 12 hyp6 ana

🔬 HNRNPA2B1 ProteinKG

protein · 5,015 words · 23 hyp8 ana12 exp

🔬 TRA2B Protein - Transformer-2 BetaKG

protein · 4,438 words · 6 hyp6 ana1 exp

🔬 nf1-proteinKG

protein · 4,422 words · 7 hyp7 ana

🔬 nlrc5-proteinKG

protein · 4,393 words · 4 hyp6 ana1 exp

🔬 Gemin-8 ProteinKG

protein · 4,111 words · 8 hyp6 ana

🔬 Beta-Secretase (BACE1) ProteinKG

protein · 3,982 words · 54 hyp24 ana5 exp

🔬 FOXO1 ProteinKG

protein · 3,787 words · 11 hyp7 ana4 exp

🔬 Kv7.3 Potassium ChannelKG

protein · 3,781 words · 7 hyp9 ana

🔬 Prion Protein (PRNP)KG

protein · 3,677 words · 58 hyp16 ana

🔬 DCTN1 Protein (Dynactin Subunit 1)KG

protein · 3,576 words · 4 hyp6 ana1 exp

🔬 Huntingtin Protein (HTT)KG

protein · 3,473 words · 10 hyp9 ana

🔬 Kv7.2 Potassium ChannelKG

protein · 3,469 words · 6 hyp9 ana

🔬 RICTOR ProteinKG

protein · 3,451 words · 5 hyp6 ana1 exp

🔬 Cytochrome c ProteinKG

protein · 3,387 words · 15 hyp13 ana2 exp

🔬 HDAC6 ProteinKG

protein · 3,384 words · 34 hyp22 ana3 exp

🔬 HDAC6 ProteinKG

protein · 3,366 words · 17 hyp6 ana3 exp

🔬 Gamma-Secretase Complex (γ-Secretase)KG

protein · 3,346 words · 13 hyp6 ana2 exp

🔬 SNX3 Protein — Sorting Nexin 3 in NeurodegenerationKG

protein · 3,294 words · 284 hyp41 ana54 exp

🔬 Prion ProteinKG

protein · 3,290 words · 5 hyp9 ana3 exp

🔬 PNMT ProteinKG

protein · 3,289 words · 6 hyp6 ana

🔬 Ataxin-3 (Josephin)KG

protein · 3,275 words · 4 hyp2 ana

🔬 FBXO3 ProteinKG

protein · 3,173 words · 4 hyp6 ana

🔬 Kinesin-1 Heavy Chain ProteinKG

protein · 3,164 words · 8 hyp6 ana

🔬 PAK2 Protein (p21-Activated Kinase 2)KG

protein · 3,160 words · 4 hyp7 ana1 exp

🔬 Flotillin-1 ProteinKG

protein · 3,155 words · 6 hyp7 ana

🔬 Beta-Synuclein ProteinKG

protein · 3,143 words · 5 hyp8 ana

🔬 Huntingtin (HTT)KG

protein · 3,134 words · 37 hyp37 ana3 exp

🔬 SOD1 ProteinKG

protein · 3,125 words · 114 hyp48 ana4 exp

🔬 GBA1 Protein (Glucocerebrosidase)KG

protein · 3,125 words · 14 hyp13 ana15 exp

🔬 GDI2 ProteinKG

protein · 3,096 words · 5 hyp7 ana

🔬 Stathmin-2 (SCG10)KG

protein · 3,087 words · 7 hyp5 ana

🔬 Gamma-Synuclein ProteinKG

protein · 3,069 words · 8 hyp9 ana1 exp

🔬 Neprilysin (NEP / CD10 / MME)KG

protein · 3,068 words · 10 hyp8 ana1 exp

🔬 Beclin-1 ProteinKG

protein · 3,061 words · 11 hyp9 ana2 exp

🔬 Gemin-6 ProteinKG

protein · 3,060 words · 8 hyp6 ana

🔬 Amyloid-Beta (Aβ)KG

protein · 3,049 words · 51 hyp11 ana16 exp

🔬 TAR DNA-Binding Protein 43 (TDP-43)KG

protein · 3,035 words · 23 hyp17 ana3 exp

🔬 ATF3 ProteinKG

protein · 3,024 words · 8 hyp8 ana

🔬 PM20D1 ProteinKG

protein · 3,010 words · 4 hyp6 ana

🔬 TDP-43 ProteinKG

protein · 3,005 words · 23 hyp22 ana27 exp

🔬 Intercellular Adhesion Molecule-5 ProteinKG

protein · 2,995 words · 6 hyp8 ana1 exp

🔬 atxn3-proteinKG

protein · 2,995 words · 7 hyp6 ana

🔬 GSK3-beta ProteinKG

protein · 2,991 words · 10 hyp10 ana

🔬 PP2A ProteinKG

protein · 2,978 words · 16 hyp22 ana

🔬 GSK3B (Glycogen Synthase Kinase 3 Beta)KG

protein · 2,976 words · 33 hyp17 ana

🔬 GSK-3βKG

protein · 2,976 words · 31 hyp14 ana

🔬 HNRNPA1 ProteinKG

protein · 2,974 words · 20 hyp11 ana

🔬 KEAP1 ProteinKG

protein · 2,974 words · 18 hyp6 ana

🔬 TMEM175 ProteinKG

protein · 2,968 words · 6 hyp8 ana

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