🧫
CRISPR Gene Correction Approaches for CBS/PSP
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-crispr-g
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.905522Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['CRISPR'], 'diseases': ["Parkinson's Disease"]} |
| model_system | human |
| summary | # CRISPR Gene Correction Approaches for CBS/PSP ## Background and Rationale CRISPR-Cas9 gene editing represents a transformative therapeutic modality for treating monogenic forms of neurodegeneration, |
| replication_status | single_study |
| methodology_notes | **Phase 1: Patient Recruitment and Screening (Months 1-6)** • Recruit 60 patients with genetically confirmed CBS/PSP (MAPT, GRN, or C9orf72 mutations) • Obtain informed consent for research participat |
| primary_outcome | Validate CRISPR Gene Correction Approaches for CBS/PSP |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.905527'} |
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