gene

CCL25

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CCL25: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections
0Hypotheses
0Analyses
19Outgoing
10Incoming
0Experiments

Summary

CCL25 is a gene implicated in neurodegeneration research. Key relationships include: biomarker for, associated with, activates. Associated with Aging, Alzheimer, Autoimmune. Connected to 26 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolCCL25
Chromosome19p13.2
Protein TypeChemokine
FunctionCCL25 has distinct functions in immune development and homeostasis:
Primary ExpressionHigh on small intestinal T cells, thymocytes, and some inflammatory cells
Molecular Weight~9.4 kDa
PathwaysPI3K, MAPK
NCBI Gene ID6374
GeneCardsCCL25
Human Protein AtlasCCL25
Protein ClassChemokine
Cell TypeExpression Level
Thymic epithelial cellsHigh
Small intestineHigh
Dendritic cellsModerate
Associated DiseasesDepression, Inflammation, Neuroinflammation
InteractionsCX3CR1, CXCR5, CX3CL1
KG Connections29 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

CCL25 Gene

gene · 1415 words

CXCR5 Gene

gene · 2217 words

Genes

index · 271 words

Pathway Diagram

graph TD
    CCL25["<b>CCL25</b>"]
    Ms{"Ms"}
    CCL25 -->|"biomarker for"| Ms
    Inflammation{"Inflammation"}
    CCL25 -->|"biomarker for"| Inflammation
    Depression{"Depression"}
    CCL25 -->|"associated with"| Depression
    Tumor{"Tumor"}
    CCL25 -->|"therapeutic target"| Tumor
    Autoimmune{"Autoimmune"}
    CCL25 -->|"therapeutic target"| Autoimmune
    INFLAMMATION["INFLAMMATION"]
    CCL25 -->|"biomarker for"| INFLAMMATION
    CXCL10["CXCL10"]
    CCL25 -->|"biomarker for"| CXCL10
    Immune_Response(["Immune Response"])
    CCL25 -->|"biomarker for"| Immune_Response
    CX3CR1["CX3CR1"]
    CCL25 -->|"activates"| CX3CR1
    neurodegeneration["neurodegeneration"]
    CCL25 -->|"implicated in"| neurodegeneration
    CCL3["CCL3"]
    CCL3 -->|"biomarker for"| CCL25
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"biomarker for"| CCL25
    CXCR5["CXCR5"]
    CXCR5 -->|"activates"| CCL25
    CX3CL1["CX3CL1"]
    CX3CL1 -->|"activates"| CCL25
    style CCL25 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (19)

TargetRelationTypeStr
Msbiomarker_fordisease0.65
Inflammationbiomarker_fordisease0.65
Depressionassociated_withdisease0.65
Tumortherapeutic_targetdisease0.65
Autoimmunetherapeutic_targetdisease0.65

Incoming (10)

SourceRelationTypeStr
CCL3biomarker_forgene0.60
CXCR5activatesgene0.60
CX3CL1activatesgene0.60
TAUregulatesgene0.60
CYTOKINESbiomarker_forgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found