concept

IL12

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

44Connections

0Hypotheses

0Analyses

31Outgoing

13Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	IL12
Key Genes/Proteins	IL35, IL30, ESR2, NR3C2, TNF, CYTOKINES
Related Diseases	Alopecia Areata, Tumor, ALS, Als

Wiki Pages (2)

Knowledge base pages for this entity

IL23A Gene

gene · 2068 words

→

IL30 — Interleukin 30 (p28 Subunit)

gene · 1804 words

→

Pathway Diagram

graph TD
    IL12["IL12"]
    IL12 -->|"component_of"| IL35["IL35"]
    IL12 -->|"involved_in"| Alopecia_Areata["Alopecia Areata"]
    IL12 -->|"expressed in"| Tumor["Tumor"]
    IL12 -->|"activates"| ALS["ALS"]
    IL12 -->|"activates"| Als["Als"]
    IL12 -->|"expressed in"| ESR2["ESR2"]
    IL12 -->|"expressed in"| NR3C2["NR3C2"]
    IL12 -->|"expressed in"| TNF["TNF"]
    AVP["AVP"] -->|"expressed in"| IL12
    ESR1["ESR1"] -->|"expressed in"| IL12
    CRH["CRH"] -->|"expressed in"| IL12
    NR3C1["NR3C1"] -->|"expressed in"| IL12
    CRHR1["CRHR1"] -->|"expressed in"| IL12
    POMC["POMC"] -->|"expressed in"| IL12
    TNF -->|"expressed in"| IL12
    ESR2 -->|"expressed in"| IL12

Outgoing (31)

Target	Relation	Type	Str
IL35	component_of	protein	0.90
IL30	associated_with	gene	0.80
Alopecia Areata	associated_with	disease	0.80
Alopecia Areata	involved_in	disease	0.75
FOXP3(lo) non-Treg cells	promotes	cell_type	0.75
Tumor	expressed_in	disease	0.65
ALS	activates	disease	0.65
Als	activates	disease	0.65
ESR2	expressed_in	gene	0.60
NR3C2	expressed_in	gene	0.60
TNF	expressed_in	gene	0.60
CYTOKINES	activates	gene	0.60
CRHR1	expressed_in	gene	0.60
CRH	expressed_in	gene	0.60
POMC	expressed_in	gene	0.60
JUN	activates	gene	0.60
NR3C1	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
AVP	expressed_in	gene	0.60
ESR1	expressed_in	gene	0.60
Immune Response	activates	pathway	0.60
Er Stress	activates	pathway	0.60
Interleukin	expressed_in	protein	0.60
Cytokine	activates	protein	0.60
Raf	activates	protein	0.60
Rb	activates	protein	0.60
IL18	associated_with	gene	0.60
IL4	associated_with	gene	0.60
IL6	associated_with	gene	0.60
TNF	associated_with	gene	0.60
oxidative stress response	participates_in	pathway	0.60

Incoming (13)

Source	Relation	Type	Str
AVP	expressed_in	gene	0.60
ESR1	expressed_in	gene	0.60
CRH	expressed_in	gene	0.60
NR3C1	expressed_in	gene	0.60
CRHR1	expressed_in	gene	0.60
POMC	expressed_in	gene	0.60
TNF	expressed_in	gene	0.60
ESR2	expressed_in	gene	0.60
JUN	activates	gene	0.60
NR3C2	expressed_in	gene	0.60
CYTOKINES	activates	gene	0.60
C5	associated_with	gene	0.60
IL10	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found