ESR2

Understanding Entity Pages

This page aggregates everything SciDEX knows about ESR2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ESR2 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, expressed in. Associated with ALS, Als, Alzheimer. Connected to 108 entities in the SciDEX knowledge graph.

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graph TD
    ESR2["ESR2"]
    ESR2 -->|"expressed in"| Tumor["Tumor"]
    ESR2 -->|"activates"| Als["Als"]
    ESR2 -->|"regulates"| Cancer["Cancer"]
    ESR2 -->|"regulates"| Cardiovascular["Cardiovascular"]
    ESR2 -->|"regulates"| Neurodegeneration["Neurodegeneration"]
    ESR2 -->|"target for"| Alzheimer["Alzheimer"]
    ESR2 -->|"target for"| Ms["Ms"]
    ESR2 -->|"activates"| ALS["ALS"]
    ESR2 -->|"activates"| Immune_Response["Immune Response"]
    ESR2 -->|"activates"| Er_Stress["Er Stress"]
    CRH["CRH"] -->|"expressed in"| ESR2
    AVP["AVP"] -->|"expressed in"| ESR2
    POMC["POMC"] -->|"expressed in"| ESR2
    CRHR1["CRHR1"] -->|"expressed in"| ESR2
    NR3C1["NR3C1"] -->|"expressed in"| ESR2
    JUN["JUN"] -->|"activates"| ESR2
    ESR1["ESR1"] -->|"expressed in"| ESR2
    TNF["TNF"] -->|"expressed in"| ESR2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"target for"| ESR2
    MAP2["MAP2"] -->|"activates"| ESR2