IL4

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

IL4 is a gene implicated in neurodegeneration research. Key relationships include: biomarker for, therapeutic target, activates. Associated with ALS, Als, Alzheimer. Connected to 89 entities in the SciDEX knowledge graph.

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flowchart TD
    IL4["IL4"] -.->|"inhibits"| CLDN1["CLDN1"]
    IL4["IL4"] -.->|"inhibits"| CLDN4["CLDN4"]
    IL4["IL4"] -.->|"inhibits"| OCLN["OCLN"]
    IL4["IL4"] -->|"biomarker for"| Neurodegeneration["Neurodegeneration"]
    IL4["IL4"] -->|"biomarker for"| Als["Als"]
    IL4["IL4"] -->|"biomarker for"| Inflammation["Inflammation"]
    IL4["IL4"] -->|"biomarker for"| Neuroinflammation["Neuroinflammation"]
    IL4["IL4"] -->|"biomarker for"| Alzheimer["Alzheimer"]
    IL4["IL4"] -->|"associated with"| Ischemia["Ischemia"]
    IL4["IL4"] -.->|"inhibits"| Ms["Ms"]
    IL4["IL4"] -->|"biomarker for"| ALS["ALS"]
    IL4["IL4"] -->|"activates"| FGF2["FGF2"]
    style IL4 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style CLDN1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style CLDN4 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style OCLN fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style Neurodegeneration fill:#ef5350,stroke:#333,color:#e0e0e0
    style Als fill:#ef5350,stroke:#333,color:#e0e0e0
    style Inflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Neuroinflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Alzheimer fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ischemia fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ms fill:#ef5350,stroke:#333,color:#e0e0e0
    style ALS fill:#ef5350,stroke:#333,color:#e0e0e0
    style FGF2 fill:#4a1a6b,stroke:#333,color:#e0e0e0