ITPR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about ITPR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for ITPR1 - Inositol 1,4,5-Trisphosphate Receptor Type 1

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graph TD
    ITPR1["<b>ITPR1</b>"]
    Atherosclerosis{"Atherosclerosis"}
    ITPR1 -->|"expressed in"| Atherosclerosis
    Diabetes{"Diabetes"}
    ITPR1 -->|"associated with"| Diabetes
    MAP1LC3B["MAP1LC3B"]
    ITPR1 -->|"expressed in"| MAP1LC3B
    GENES["GENES"]
    ITPR1 -->|"expressed in"| GENES
    TIMP1["TIMP1"]
    ITPR1 -->|"expressed in"| TIMP1
    Autophagy(["Autophagy"])
    ITPR1 -->|"expressed in"| Autophagy
    WIPI1["WIPI1"]
    ITPR1 -->|"associated with"| WIPI1
    ITPR1 -->|"associated with"| Autophagy
    Mitophagy(["Mitophagy"])
    ITPR1 -->|"associated with"| Mitophagy
    AND["AND"]
    ITPR1 -->|"expressed in"| AND
    AUTOPHAGY["AUTOPHAGY"]
    ITPR1 -->|"expressed in"| AUTOPHAGY
    neurodegeneration["neurodegeneration"]
    ITPR1 -->|"implicated in"| neurodegeneration
    IL12B["IL12B"]
    IL12B -->|"expressed in"| ITPR1
    RAB7A["RAB7A"]
    RAB7A -->|"associated with"| ITPR1
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"associated with"| ITPR1
    GABARAPL2["GABARAPL2"]
    GABARAPL2 -->|"associated with"| ITPR1
    FOXO3["FOXO3"]
    FOXO3 -->|"associated with"| ITPR1
    LAMP2["LAMP2"]
    LAMP2 -->|"associated with"| ITPR1
    DIABETES_MELLITUS["DIABETES MELLITUS"]
    DIABETES_MELLITUS -->|"associated with"| ITPR1
    RB1CC1["RB1CC1"]
    RB1CC1 -->|"associated with"| ITPR1
    AUTOPHAGY -->|"associated with"| ITPR1
    EIF2AK3["EIF2AK3"]
    EIF2AK3 -->|"associated with"| ITPR1
    GAPDH["GAPDH"]
    GAPDH -->|"associated with"| ITPR1
    AUTOPHAGY_RELATED_GENES["AUTOPHAGY-RELATED GENES"]
    AUTOPHAGY_RELATED_GENES -->|"associated with"| ITPR1
    style ITPR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0