protein

LDL RECEPTOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LDL RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections
0Hypotheses
0Analyses
16Outgoing
13Incoming

Summary

Page for LDL Receptor Protein

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🔬 Protein Info
Gene SymbolLDL RECEPTOR
Amino Acids40 aa
PathwaysCholesterol
Associated DiseasesAlzheimer'S Disease, disease
InteractionsLDLR, GPR146
KG Connections29 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (20)

Knowledge base pages for this entity

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

Astrocyte Reactivity Mechanism

mechanism · 5036 words

Blood-Brain Barrier Biology and Crossing Strategies

mechanism · 4474 words

Niemann-Pick Disease Type C (NPC)

disease · 4341 words

PEN2 Gene

gene · 4033 words

Pathway Diagram

graph TD
    LDL_RECEPTOR["<b>LDL RECEPTOR</b>"]
    Proteins["Proteins"]
    LDL_RECEPTOR -->|"associated with"| Proteins
    ALZHEIMER["ALZHEIMER"]
    LDL_RECEPTOR -->|"associated with"| ALZHEIMER
    Alzheimer_S_Disease["Alzheimer'S Disease"]
    LDL_RECEPTOR -->|"associated with"| Alzheimer_S_Disease
    disease["disease"]
    LDL_RECEPTOR -->|"associated with"| disease
    ALZHEIMER_S["ALZHEIMER'S"]
    LDL_RECEPTOR -->|"associated with"| ALZHEIMER_S
    PCSK9["PCSK9"]
    LDL_RECEPTOR -->|"activates"| PCSK9
    Cholesterol["Cholesterol"]
    LDL_RECEPTOR -->|"inhibits"| Cholesterol
    atherosclerosis["atherosclerosis"]
    LDL_RECEPTOR -->|"inhibits"| atherosclerosis
    Macrophage["Macrophage"]
    LDL_RECEPTOR -->|"inhibits"| Macrophage
    MACROPHAGES["MACROPHAGES"]
    LDL_RECEPTOR -->|"inhibits"| MACROPHAGES
    Cholesterol["Cholesterol"]
    LDL_RECEPTOR -->|"expressed in"| Cholesterol
    atherosclerosis["atherosclerosis"]
    LDL_RECEPTOR -->|"expressed in"| atherosclerosis
    Macrophage["Macrophage"]
    LDL_RECEPTOR -->|"expressed in"| Macrophage
    MACROPHAGES["MACROPHAGES"]
    LDL_RECEPTOR -->|"expressed in"| MACROPHAGES
    APP_PS1["APP/PS1"]
    LDL_RECEPTOR -->|"inhibits"| APP_PS1
    Genes["Genes"]
    LDL_RECEPTOR -->|"associated with"| Genes
    VESICLE_TRAFFICKING["VESICLE TRAFFICKING"]
    LDL_RECEPTOR -->|"associated with"| VESICLE_TRAFFICKING
    LRP1["LRP1"]
    LRP1 -->|"associated with"| LDL_RECEPTOR
    LDLR["LDLR"]
    LDLR -->|"associated with"| LDL_RECEPTOR
    LRP4["LRP4"]
    LRP4 -->|"associated with"| LDL_RECEPTOR
    LRP8["LRP8"]
    LRP8 -->|"associated with"| LDL_RECEPTOR
    LRP5["LRP5"]
    LRP5 -->|"associated with"| LDL_RECEPTOR
    LRP1B["LRP1B"]
    LRP1B -->|"associated with"| LDL_RECEPTOR
    LRP2["LRP2"]
    LRP2 -->|"associated with"| LDL_RECEPTOR
    APOER2["APOER2"]
    APOER2 -->|"associated with"| LDL_RECEPTOR
    late["late"]
    late -->|"associated with"| LDL_RECEPTOR
    LDLR["LDLR"]
    LDLR -->|"activates"| LDL_RECEPTOR
    LDLR["LDLR"]
    LDLR -->|"inhibits"| LDL_RECEPTOR
    GPR146["GPR146"]
    GPR146 -->|"inhibits"| LDL_RECEPTOR
    FASN["FASN"]
    FASN -->|"associated with"| LDL_RECEPTOR

Outgoing (16)

TargetRelationTypeStr
Proteinsassociated_withprotein0.50
ALZHEIMERassociated_withgene0.50
Alzheimer'S Diseaseassociated_withdisease0.50
diseaseassociated_withdisease0.50
ALZHEIMER'Sassociated_withconcept0.50

Incoming (15)

SourceRelationTypeStr
LRP1associated_withgene0.50
LDLRassociated_withgene0.50
LRP4associated_withgene0.50
LRP8associated_withgene0.50
LRP5associated_withgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found