LRP8

Understanding Entity Pages

This page aggregates everything SciDEX knows about LRP8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

LRP8 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, regulates. Associated with ALS, Aging, Als. Connected to 66 entities in the SciDEX knowledge graph.

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graph TD
    LRP8["<b>LRP8</b>"]
    Cancer{"Cancer"}
    LRP8 -->|"associated with"| Cancer
    Neurodegeneration{"Neurodegeneration"}
    LRP8 -->|"associated with"| Neurodegeneration
    Cardiovascular{"Cardiovascular"}
    LRP8 -->|"associated with"| Cardiovascular
    Als{"Als"}
    LRP8 -->|"associated with"| Als
    Aging{"Aging"}
    LRP8 -->|"associated with"| Aging
    Hypertension{"Hypertension"}
    LRP8 -->|"associated with"| Hypertension
    Atherosclerosis{"Atherosclerosis"}
    LRP8 -->|"associated with"| Atherosclerosis
    Stroke{"Stroke"}
    LRP8 -->|"associated with"| Stroke
    Ms{"Ms"}
    LRP8 -->|"associated with"| Ms
    Heart_Failure{"Heart Failure"}
    LRP8 -->|"associated with"| Heart_Failure
    Ftd{"Ftd"}
    LRP8 -->|"associated with"| Ftd
    ALS{"ALS"}
    LRP8 -->|"associated with"| ALS
    LRP1B["LRP1B"]
    LRP1B -->|"associated with"| LRP8
    PAH["PAH"]
    PAH -->|"associated with"| LRP8
    LRP4["LRP4"]
    LRP4 -->|"associated with"| LRP8
    LDLR["LDLR"]
    LDLR -->|"associated with"| LRP8
    LRP5["LRP5"]
    LRP5 -->|"associated with"| LRP8
    LRP1["LRP1"]
    LRP1 -->|"associated with"| LRP8
    LDL["LDL"]
    LDL -->|"associated with"| LRP8
    STROKE["STROKE"]
    STROKE -->|"associated with"| LRP8
    LRP2["LRP2"]
    LRP2 -->|"associated with"| LRP8
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"associated with"| LRP8
    CANCER["CANCER"]
    CANCER -->|"associated with"| LRP8
    REELIN["REELIN"]
    REELIN -->|"associated with"| LRP8
    style LRP8 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0