Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RASSF1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
RASSF1A["RASSF1A"]
RASSF1A -->|"regulates"| Cardiovascular["Cardiovascular"]
RASSF1A -->|"activates"| Ms["Ms"]
RASSF1A -->|"activates"| Als["Als"]
RASSF1A -->|"inhibits"| Tumor["Tumor"]
RASSF1A -->|"inhibits"| AND["AND"]
RASSF1A -->|"inhibits"| GENES["GENES"]
RASSF1A -->|"activates"| HIPPO["HIPPO"]
RASSF1A -->|"activates"| AKT["AKT"]
MET["MET"] -->|"activates"| RASSF1A
ONCOGENES["ONCOGENES"] -->|"activates"| RASSF1A
MAPK["MAPK"] -->|"activates"| RASSF1A
EGFR["EGFR"] -->|"activates"| RASSF1A
P16["P16"] -->|"inhibits"| RASSF1A| Target | Relation | Type | Str |
|---|---|---|---|
| Als | activates | disease | 0.65 |
| Tumor | inhibits | disease | 0.65 |
| Ms | activates | disease | 0.65 |
| AKT | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
| NF2 | inhibits | gene | 0.60 |
| RAS | inhibits | gene | 0.60 |
| PIK3CA | activates | gene | 0.60 |
| Pi3K | activates | pathway | 0.60 |
| Akt | activates | pathway | 0.60 |
| Epigenetic | inhibits | pathway | 0.60 |
| AND | inhibits | gene | 0.60 |
| Mapk | activates | pathway | 0.60 |
| GENES | inhibits | gene | 0.60 |
| HIPPO | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity