XPA

Understanding Entity Pages

This page aggregates everything SciDEX knows about XPA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

XPA is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, implicated in. Associated with Aging, Als, Ms. Connected to 20 entities in the SciDEX knowledge graph.

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graph TD
    XPA["<b>XPA</b>"]
    Senescence{"Senescence"}
    XPA -->|"activates"| Senescence
    Aging{"Aging"}
    XPA -->|"regulates"| Aging
    Als{"Als"}
    XPA -->|"activates"| Als
    Ms{"Ms"}
    XPA -->|"regulates"| Ms
    Tumor{"Tumor"}
    XPA -->|"activates"| Tumor
    CLOCK["CLOCK"]
    XPA -->|"activates"| CLOCK
    AUTOPHAGY["AUTOPHAGY"]
    XPA -->|"regulates"| AUTOPHAGY
    PDIA3["PDIA3"]
    XPA -->|"activates"| PDIA3
    BMAL1["BMAL1"]
    XPA -->|"regulates"| BMAL1
    AHR["AHR"]
    XPA -->|"regulates"| AHR
    CIRCADIAN_RHYTHM["CIRCADIAN RHYTHM"]
    XPA -->|"regulates"| CIRCADIAN_RHYTHM
    Autophagy(["Autophagy"])
    XPA -->|"regulates"| Autophagy
    AGING["AGING"]
    AGING -->|"regulates"| XPA
    MTOR["MTOR"]
    MTOR -->|"regulates"| XPA
    MYC["MYC"]
    MYC -->|"activates"| XPA
    NF__B["NF-KappaB"]
    NF__B -->|"regulates"| XPA
    style XPA fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0