| Gene Symbol | BCHE |
| Aliases | Page for BCHE Gene |
| Chromosome | 3q26.1 |
| Protein Type | Hydrolase |
| Function | Unlike acetylcholinesterase (AChE), which is primarily localized at neuronal synapses, BuChE is found in: - Plasma — the major source of circulating BuChE - Liver — primary site of synthesis - Brain — |
| Primary Expression | Liver, Brain (cerebral cortex, hippocampus, basal forebrain), Serum |
| Subcellular Localization | neuronal synapses, BuChE is found in: |
| Amino Acids | 574 aa |
| Exons | 4 |
| Pathways | autophagy pathway |
| UniProt ID | P06276 |
| NCBI Gene ID | 163 |
| Ensembl ID | ENSG00000114200 |
| OMIM | 177400 |
| GeneCards | BCHE |
| Human Protein Atlas | BCHE |
| Associated Diseases | Alzheimer, Alzheimer'S Disease, Anxiety, Dementia, Depression |
| Known Drugs/Compounds | antidementia drugs |
| Interactions | BACE1, CHRFAM7A, CNTN1, ESR1, GABRB3, MAPT |
| KG Connections | 156 knowledge graph edges |
| Databases | GeneCardsHPASTRING |