gene 809 words KG: CDK2
Contents

CDK2 Gene

🧬 Gene Info
Gene SymbolCDK2
Full NameCyclin-Dependent Kinase 2
Chromosome12q13.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight34 kDa
Amino Acids297 aa
Exons9
PathwaysCell Cycle, Cell Division
UniProt IDP24941
NCBI Gene ID1017
Ensembl IDENSG00000145386
GeneCardsCDK2
Human Protein AtlasCDK2
Associated DiseasesAging, ALS, Cancer, Gastric Cancer, Ms, Neurodegeneration
Known Drugs/CompoundsThiabendazole
InteractionsActin, AGING, AKT, AND, APC, App
KG Connections241 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: interacts_with
APC Gene
gene · KG edge: activates
ATF2 — Activating Transcription Factor 2
gene · KG edge: activates
BAX Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

JUN activates CDK2
CDK2 activates APC
JUN inhibits CDK2
APC activates CDK2
CDK2 inhibits JUN
FYN associated_with CDK2
MAPK3 associated_with CDK2
PAK1 associated_with CDK2
CDK2 associated_with MAP1LC3B
CDK2 associated_with GNAQ

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