gene 1,846 words KG: TNFRSF13C 2026-03-27
kind:genesection:genesstate:published
Contents

BAFFR Gene (TNFRSF13C)

🧬 Gene Info
Gene SymbolTNFRSF13C
Full NameTNF Receptor Superfamily Member 13C
Chromosome22q12.1
Protein FamilyTNF receptor superfamily
Protein TypeReceptor
Functionis a critical member of the TNF receptor superfamily that plays an essential and non-redundant role in B cell survival, maturation, and homeostasis.
Exons5
PathwaysWnt
UniProt IDQ9Y239
NCBI Gene ID115650
Ensembl IDENSG00000159958
OMIM606269
GeneCardsTNFRSF13C
Human Protein AtlasTNFRSF13C
Alternative NamesBAFFR, BR3, CD268
Associated DiseasesAtaxia, Neurodegeneration, Spinocerebellar Ataxia, disease
InteractionsHCRTR1, CHRM4, MYO7A, ADRA2B, GRM2, CRH
KG Connections66 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Oligodendrocyte White Matter Vulnerability
Score: 0.40
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: activates
MYO7A — Myosin VIIa
gene · KG edge: activates
IL13 — Interleukin 13
gene · KG edge: activates
HCRTR1
gene · KG edge: activates
GRM2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

TNFRSF13C activates HCRTR1
TNFRSF13C associated_with SCA3
TNFRSF13C expressed_in Brainstem
TNFRSF13C associated_with ATXN3
TNFRSF13C expressed_in Ca3
TNFRSF13C activates CHRM4
TNFRSF13C activates MYO7A
TNFRSF13C activates ADRA2B
TNFRSF13C activates GRM2
TNFRSF13C encodes SCA3