gene 689 words KG: JUN
Contents

JUN Gene

🧬 Gene Info
Gene SymbolJUN
Full NameJun Proto-Oncogene, AP-1 Transcription Factor Subunit
Chromosome1p32.1
Protein TypeTranscription Factor
Functionc-Jun/AP-1 is a key transcription factor
Primary Expressionproliferating neural progenitors and migrating neurons, declining to lower basal levels in the adult brain
PathwaysAkt, Amyloid, Apoptosis, Autophagy, Blood-Brain Barrier
UniProt IDP45985
NCBI Gene ID3715
Ensembl IDENSG00000100994
OMIM165160
GeneCardsJUN
Human Protein AtlasJUN
Associated DiseasesAddiction, Aging, Als, Alzheimer, Alzheimer's disease
Known Drugs/Compoundsanti-CD3, burn serum, pokeweed mitogen, quercetin
InteractionsABCA1, ABCB1, ACSL5, ACTB, Actin, AGING
KG Connections2425 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

JUN contributes_to AP1
JUN inhibits HCN1
JUN therapeutic_target SLC16A2
JUN inhibits HCN4
JUN protects_against APOE
JUN protects_against RELN
JUN regulates DAB1
JUN regulates FYN
JUN regulates SRC
JUN inhibits HCN2

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