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mechanism 562 words KG: AD
Contents

psilocybin-neuropsychiatric-ad

⚙ Mechanism Info
NameAD
Key Genes/ProteinsTAU, BETA_AMYLOID, PHOSPHORYLATED_TAU, SOD1
Related Diseasesneurodegeneration, memory_loss, IMMUNE_TOL, DEMENTIA
Related Pathwayscholinergic_transmission, PROTEOME, CHOLINERGIC_TRANSMISSION
Linked Hypotheses71 hypotheses

Knowledge Graph

Related Hypotheses (30)

Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.42Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59PARP1 Inhibition Therapy
Score: 0.58Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (30)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedSEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

See Also (14)

Tau Consortium
organization · KG edge: associated_withProteome Atlas for Neurodegenerative Diseases
mechanism · KG edge: regulatesAge-Sensitive Cortical Vulnerability in Parkinson's Dis
mechanism · KG edge: associated_withPackard Center for ALS Research
institution · KG edge: implicated_inDementia Australia
institution · KG edge: causes

Knowledge Graph (12 edges)

AD causes neurodegeneration
AD inhibits cholinergic_transmission
AD causes memory_loss
AD associated_with TAU
AD regulates PROTEOME
AD associated_with GLYCOLYTIC_PATHWAY
AD causes IMMUNE_TOL
AD causes DEMENTIA
AD associated_with CHOLINERGIC_TRANSMISSION
TAU associated_with AD
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