| Gene Symbol | EGFR |
| Chromosome | 7 |
| Protein Family | ErbB/EGFR tyrosine kinase family |
| Protein Type | Receptor |
| Function | EGFR (Epidermal Growth Factor Receptor) is a receptor tyrosine kinase that binds EGF, TGF-α, and other ligands. |
| Primary Expression | neural stem cells, astrocytes, and neurons, where it regulates neurogenesis, gliogenesis, synaptic plasti |
| Molecular Weight | 134.3 kDa |
| Pathways | Akt, Apoptosis, Autophagy, Camp Signaling, Cell Cycle |
| UniProt ID | [P00533](https://www.uniprot.org/uniprot/P00533) |
| GeneCards | EGFR |
| Human Protein Atlas | EGFR |
| Associated Diseases | AD, ADH, ALS, AMI, Aging |
| Known Drugs/Compounds | EGFR-TKI, RAPAMYCIN, QUERCETIN, tyrosine kinase inhibitors, monoclonal antibodies, amivantamab |
| Interactions | PPARG, HSPA5, MAVS, FIP200, AMBRA1, APC |
| KG Connections | 2660 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |