concept

CARM1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CARM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

44Connections

0Hypotheses

0Analyses

32Outgoing

12Incoming

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💡 Concept Info

Name	CARM1
Key Genes/Proteins	UBIQUITIN, AND, Ras, HTT
Related Diseases	Ms, Heart Failure, Cardiac, MITOPHAGY, AUTOPHAGY
Related Pathways	mitophagy, autophagy, Autophagy, Mitophagy

Pathway Diagram

graph TD
    CARM1["CARM1"]
    CARM1 -->|"activates"| mitophagy["mitophagy"]
    CARM1 -->|"activates"| autophagy["autophagy"]
    CARM1 -->|"activates"| Ms["Ms"]
    CARM1 -->|"activates"| Heart_Failure["Heart Failure"]
    CARM1 -->|"target for"| Cardiac["Cardiac"]
    CARM1 -->|"regulates"| skeletal_muscle["skeletal_muscle"]
    CARM1 -->|"activates"| MITOPHAGY["MITOPHAGY"]
    CARM1 -->|"activates"| AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"activates"| CARM1
    MITOPHAGY -->|"activates"| CARM1
    STAT3["STAT3"] -->|"activates"| CARM1
    ANG["ANG"] -->|"activates"| CARM1
    AND["AND"] -->|"activates"| CARM1

Outgoing (32)

Target	Relation	Type	Str
MITOPHAGY	drives	process	0.80
mitophagy	activates	pathway	0.72
autophagy	activates	pathway	0.72
Ms	activates	disease	0.65
Heart Failure	activates	disease	0.65
Cardiac	therapeutic_target	disease	0.65
skeletal_muscle	regulates	cell_type	0.64
MITOPHAGY	activates	phenotype	0.64
AUTOPHAGY	activates	phenotype	0.64
Autophagy	activates	pathway	0.60
Mitophagy	activates	pathway	0.60
UBIQUITIN	activates	gene	0.60
AND	activates	gene	0.60
Ras	regulates	protein	0.60
HTT	associated_with	gene	0.60
PRMT4	associated_with	gene	0.60
MUSCLE_ATROPHY	activates	phenotype	0.56
PRMT1	targets	gene	0.55
TDP-43	targets	gene	0.55
PRMT1	associated_with	gene	0.55
TDP-43	associated_with	gene	0.55
PRMT1	activates	gene	0.55
neurodegeneration	associated_with	disease	0.55
TDP-43	activates	gene	0.55
PRMT1	interacts_with	gene	0.55
RNA	interacts_with	gene	0.55
TDP-43	interacts_with	gene	0.55
TARDBP	activates	gene	0.55
neurons	expressed_in	cell_type	0.55
neurodegeneration	activates	disease	0.55
insulin signaling	participates_in	pathway	0.55
autophagy pathway	participates_in	pathway	0.55

Incoming (12)

Source	Relation	Type	Str
AUTOPHAGY	activates	gene	0.60
CASP8	associated_with	gene	0.60
CASP3	associated_with	gene	0.60
PPARG	associated_with	gene	0.60
ATM	associated_with	gene	0.60
MITOPHAGY	activates	gene	0.60
STAT3	activates	gene	0.60
ANG	activates	gene	0.60
AND	activates	gene	0.60
ALS	activates	gene	0.55
trehalose	targets	drug	0.55
rapamycin	targets	drug	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found