CELF2

Understanding Entity Pages

This page aggregates everything SciDEX knows about CELF2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CELF2 (CUGBP Elav-Like Family Member 2) is an RNA-binding protein that regulates alternative splicing, translation, and mRNA stability. Associated with Alzheimer's disease, ALS, and epilepsy.

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graph TD
    CELF2["<b>CELF2</b>"]
    Alzheimer{"Alzheimer"}
    CELF2 -->|"expressed in"| Alzheimer
    Aging{"Aging"}
    CELF2 -->|"expressed in"| Aging
    Als{"Als"}
    CELF2 -->|"expressed in"| Als
    Ms{"Ms"}
    CELF2 -->|"expressed in"| Ms
    Dementia{"Dementia"}
    CELF2 -->|"expressed in"| Dementia
    JUN["JUN"]
    CELF2 -->|"expressed in"| JUN
    Autophagy(["Autophagy"])
    CELF2 -->|"expressed in"| Autophagy
    neurodegeneration["neurodegeneration"]
    CELF2 -->|"implicated in"| neurodegeneration
    FYN["FYN"]
    FYN -->|"expressed in"| CELF2
    AGING["AGING"]
    AGING -->|"expressed in"| CELF2
    VCP["VCP"]
    VCP -->|"expressed in"| CELF2
    CTNNB1["CTNNB1"]
    CTNNB1 -->|"expressed in"| CELF2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"expressed in"| CELF2
    EGFR["EGFR"]
    EGFR -->|"expressed in"| CELF2
    HSP90AA1["HSP90AA1"]
    HSP90AA1 -->|"expressed in"| CELF2
    APP["APP"]
    APP -->|"expressed in"| CELF2
    HSP90AB1["HSP90AB1"]
    HSP90AB1 -->|"expressed in"| CELF2
    MDM2["MDM2"]
    MDM2 -->|"expressed in"| CELF2
    HSF1["HSF1"]
    HSF1 -->|"expressed in"| CELF2
    GRB2["GRB2"]
    GRB2 -->|"expressed in"| CELF2
    style CELF2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0