DUSP6

Understanding Entity Pages

This page aggregates everything SciDEX knows about DUSP6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DUSP6 is a gene implicated in neurodegeneration research. Key relationships include: inhibits, regulates, activates. Associated with Aging, Als, Fibrosis. Connected to 32 entities in the SciDEX knowledge graph.

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graph TD
    DUSP6["<b>DUSP6</b>"]
    Parkinson{"Parkinson"}
    DUSP6 -->|"inhibits"| Parkinson
    Ms{"Ms"}
    DUSP6 -->|"inhibits"| Ms
    Fibrosis{"Fibrosis"}
    DUSP6 -->|"therapeutic target"| Fibrosis
    Als{"Als"}
    DUSP6 -->|"regulates"| Als
    Aging{"Aging"}
    DUSP6 -->|"therapeutic target"| Aging
    DUSP6 -->|"activates"| Als
    DRP1["DRP1"]
    DUSP6 -->|"inhibits"| DRP1
    LRRK2["LRRK2"]
    DUSP6 -->|"inhibits"| LRRK2
    BMI1["BMI1"]
    DUSP6 -->|"regulates"| BMI1
    CEBPB["CEBPB"]
    DUSP6 -->|"regulates"| CEBPB
    Tgf__(["Tgf-Beta"])
    DUSP6 -->|"therapeutic target"| Tgf__
    ERK1["ERK1"]
    DUSP6 -->|"activates"| ERK1
    STX17["STX17"]
    STX17 -->|"inhibits"| DUSP6
    LRRK2 -->|"inhibits"| DUSP6
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"inhibits"| DUSP6
    DRP1 -->|"inhibits"| DUSP6
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"inhibits"| DUSP6
    AGING["AGING"]
    AGING -->|"therapeutic target"| DUSP6
    FOS["FOS"]
    FOS -->|"regulates"| DUSP6
    HK2["HK2"]
    HK2 -->|"therapeutic target"| DUSP6
    LGALS3["LGALS3"]
    LGALS3 -->|"regulates"| DUSP6
    RELA["RELA"]
    RELA -->|"regulates"| DUSP6
    SOD2["SOD2"]
    SOD2 -->|"regulates"| DUSP6
    FGF21["FGF21"]
    FGF21 -->|"regulates"| DUSP6
    style DUSP6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0