BMI1

Understanding Entity Pages

This page aggregates everything SciDEX knows about BMI1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

BMI1 is a gene implicated in neurodegeneration research. Key relationships include: inhibits, regulates, therapeutic target. Associated with Aging, Als, Amyotrophic Lateral Sclerosis. Connected to 34 entities in the SciDEX knowledge graph.

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graph TD
    BMI1["<b>BMI1</b>"]
    Cancer{"Cancer"}
    BMI1 -->|"activates"| Cancer
    Als{"Als"}
    BMI1 -->|"activates"| Als
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    BMI1 -->|"activates"| Amyotrophic_Lateral_Sclerosis
    Fibrosis{"Fibrosis"}
    BMI1 -->|"therapeutic target"| Fibrosis
    BMI1 -->|"regulates"| Als
    Aging{"Aging"}
    BMI1 -->|"therapeutic target"| Aging
    CEBPB["CEBPB"]
    BMI1 -->|"regulates"| CEBPB
    Tgf__(["Tgf-Beta"])
    BMI1 -->|"therapeutic target"| Tgf__
    neurodegeneration["neurodegeneration"]
    BMI1 -->|"implicated in"| neurodegeneration
    AGING["AGING"]
    AGING -->|"therapeutic target"| BMI1
    FOS["FOS"]
    FOS -->|"regulates"| BMI1
    HK2["HK2"]
    HK2 -->|"therapeutic target"| BMI1
    LGALS3["LGALS3"]
    LGALS3 -->|"regulates"| BMI1
    RELA["RELA"]
    RELA -->|"regulates"| BMI1
    SOD2["SOD2"]
    SOD2 -->|"regulates"| BMI1
    FGF21["FGF21"]
    FGF21 -->|"regulates"| BMI1
    DUSP6["DUSP6"]
    DUSP6 -->|"regulates"| BMI1
    style BMI1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0