NPRL2

Understanding Entity Pages

This page aggregates everything SciDEX knows about NPRL2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NPRL2 is a gene implicated in neurodegeneration research. Key relationships include: activates, interacts with, implicated in. Associated with ALS, Als, Cancer. Connected to 18 entities in the SciDEX knowledge graph.

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graph TD
    NPRL2["<b>NPRL2</b>"]
    Cancer{"Cancer"}
    NPRL2 -->|"activates"| Cancer
    Tumor{"Tumor"}
    NPRL2 -->|"activates"| Tumor
    Als{"Als"}
    NPRL2 -->|"activates"| Als
    ALS{"ALS"}
    NPRL2 -->|"activates"| ALS
    CUL3["CUL3"]
    NPRL2 -->|"activates"| CUL3
    DEPDC5["DEPDC5"]
    NPRL2 -->|"interacts with"| DEPDC5
    NPRL3["NPRL3"]
    NPRL2 -->|"interacts with"| NPRL3
    Mtor(["Mtor"])
    NPRL2 -->|"activates"| Mtor
    LYSOSOME["LYSOSOME"]
    NPRL2 -->|"activates"| LYSOSOME
    UBIQUITIN["UBIQUITIN"]
    NPRL2 -->|"activates"| UBIQUITIN
    MTORC1["MTORC1"]
    NPRL2 -->|"activates"| MTORC1
    CANCER["CANCER"]
    NPRL2 -->|"activates"| CANCER
    NPRL3 -->|"interacts with"| NPRL2
    DEPDC5 -->|"interacts with"| NPRL2
    CUL3 -->|"activates"| NPRL2
    AND["AND"]
    AND -->|"interacts with"| NPRL2
    UBIQUITIN -->|"activates"| NPRL2
    MTORC1 -->|"activates"| NPRL2
    style NPRL2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0