TSC1

Understanding Entity Pages

This page aggregates everything SciDEX knows about TSC1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TSC1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, interacts with, expressed in. Associated with Aging, Als, Atherosclerosis. Connected to 124 entities in the SciDEX knowledge graph.

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graph TD
    TSC1["<b>TSC1</b>"]
    TSC2["TSC2"]
    TSC1 -->|"interacts with"| TSC2
    mTOR_signaling(["mTOR signaling"])
    TSC1 -->|"regulates"| mTOR_signaling
    mTOR["mTOR"]
    TSC1 -->|"inhibits"| mTOR
    Leukemia{"Leukemia"}
    TSC1 -->|"regulates"| Leukemia
    Als{"Als"}
    TSC1 -->|"regulates"| Als
    TSC1 -->|"interacts with"| Als
    Ms{"Ms"}
    TSC1 -->|"interacts with"| Ms
    Autism{"Autism"}
    TSC1 -->|"regulates"| Autism
    Tumor{"Tumor"}
    TSC1 -->|"regulates"| Tumor
    TSC1 -->|"therapeutic target"| Ms
    Carcinoma{"Carcinoma"}
    TSC1 -->|"interacts with"| Carcinoma
    TSC1 -->|"inhibits"| Als
    TSC2 -->|"inhibits"| TSC1
    ATF4["ATF4"]
    ATF4 -->|"regulates"| TSC1
    TSC2 -->|"regulates"| TSC1
    PTEN["PTEN"]
    PTEN -->|"regulates"| TSC1
    PI3K["PI3K"]
    PI3K -->|"regulates"| TSC1
    TSC2 -->|"interacts with"| TSC1
    TFEB["TFEB"]
    TFEB -->|"regulates"| TSC1
    TFEB -->|"therapeutic target"| TSC1
    AGING["AGING"]
    AGING -->|"associated with"| TSC1
    style TSC1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0