PANK2

Understanding Entity Pages

This page aggregates everything SciDEX knows about PANK2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PANK2 is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, regulates. Associated with Aging, Als, Dystonia. Connected to 28 entities in the SciDEX knowledge graph.

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graph TD
    PANK2["<b>PANK2</b>"]
    pantothenate_kinase_associated_neurodege{"pantothenate kinase-associated neurodegeneration"}
    PANK2 -->|"associated with"| pantothenate_kinase_associated_neurodege
    Neurodegeneration{"Neurodegeneration"}
    PANK2 -->|"associated with"| Neurodegeneration
    Ms{"Ms"}
    PANK2 -->|"associated with"| Ms
    Als{"Als"}
    PANK2 -->|"associated with"| Als
    Parkinson{"Parkinson"}
    PANK2 -->|"associated with"| Parkinson
    Dystonia{"Dystonia"}
    PANK2 -->|"associated with"| Dystonia
    Aging{"Aging"}
    PANK2 -->|"therapeutic target"| Aging
    PANK2 -->|"therapeutic target"| Als
    PLA2G6["PLA2G6"]
    PANK2 -->|"associated with"| PLA2G6
    Lipid_Metabolism(["Lipid Metabolism"])
    PANK2 -->|"associated with"| Lipid_Metabolism
    Mitophagy(["Mitophagy"])
    PANK2 -->|"associated with"| Mitophagy
    Autophagy(["Autophagy"])
    PANK2 -->|"associated with"| Autophagy
    AKT["AKT"]
    AKT -->|"regulates"| PANK2
    PLA2G6 -->|"associated with"| PANK2
    FTL["FTL"]
    FTL -->|"associated with"| PANK2
    WDR45["WDR45"]
    WDR45 -->|"associated with"| PANK2
    COASY["COASY"]
    COASY -->|"associated with"| PANK2
    DCAF17["DCAF17"]
    DCAF17 -->|"associated with"| PANK2
    FA2H["FA2H"]
    FA2H -->|"associated with"| PANK2
    C19ORF12["C19ORF12"]
    C19ORF12 -->|"associated with"| PANK2
    style PANK2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0