RBPJ

Understanding Entity Pages

This page aggregates everything SciDEX knows about RBPJ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

RBPJ is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, implicated in. Associated with Als, Cancer, Cardiovascular. Connected to 16 entities in the SciDEX knowledge graph.

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graph TD
    RBPJ["<b>RBPJ</b>"]
    Als{"Als"}
    RBPJ -->|"regulates"| Als
    Cardiovascular{"Cardiovascular"}
    RBPJ -->|"regulates"| Cardiovascular
    Cancer{"Cancer"}
    RBPJ -->|"activates"| Cancer
    CGAS["CGAS"]
    RBPJ -->|"regulates"| CGAS
    DNMT3A["DNMT3A"]
    RBPJ -->|"regulates"| DNMT3A
    LRP6["LRP6"]
    RBPJ -->|"regulates"| LRP6
    NOTCH1["NOTCH1"]
    RBPJ -->|"regulates"| NOTCH1
    Akt(["Akt"])
    RBPJ -->|"activates"| Akt
    Notch(["Notch"])
    RBPJ -->|"regulates"| Notch
    neurodegeneration["neurodegeneration"]
    RBPJ -->|"implicated in"| neurodegeneration
    SNCA["SNCA"]
    SNCA -->|"contributes to"| RBPJ
    TET2["TET2"]
    TET2 -->|"regulates"| RBPJ
    TFAM["TFAM"]
    TFAM -->|"regulates"| RBPJ
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"regulates"| RBPJ
    AKT1["AKT1"]
    AKT1 -->|"activates"| RBPJ
    CANCER["CANCER"]
    CANCER -->|"activates"| RBPJ
    style RBPJ fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0