STIM1

Understanding Entity Pages

This page aggregates everything SciDEX knows about STIM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

STIM1 is a gene implicated in neurodegeneration research. Key relationships include: activates, binds, inhibits. Associated with Inflammation, Ms, Multiple Sclerosis. Connected to 24 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    STIM1["<b>STIM1</b>"]
    STING1["STING1"]
    STIM1 -->|"binds"| STING1
    STING["STING"]
    STIM1 -->|"binds"| STING
    STIM1 -->|"inhibits"| STING
    Neurodegeneration{"Neurodegeneration"}
    STIM1 -->|"activates"| Neurodegeneration
    Multiple_Sclerosis{"Multiple Sclerosis"}
    STIM1 -->|"activates"| Multiple_Sclerosis
    Ms{"Ms"}
    STIM1 -->|"activates"| Ms
    Inflammation{"Inflammation"}
    STIM1 -->|"activates"| Inflammation
    STIM1 -->|"activates"| STING
    GPX4["GPX4"]
    STIM1 -->|"activates"| GPX4
    Ferroptosis(["Ferroptosis"])
    STIM1 -->|"activates"| Ferroptosis
    FERROPTOSIS["FERROPTOSIS"]
    STIM1 -->|"activates"| FERROPTOSIS
    Glutamate_Signaling(["Glutamate Signaling"])
    STIM1 -->|"activates"| Glutamate_Signaling
    EXCITOTOXICITY["EXCITOTOXICITY"]
    EXCITOTOXICITY -->|"causes"| STIM1
    GPX4 -->|"activates"| STIM1
    GENES["GENES"]
    GENES -->|"activates"| STIM1
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"activates"| STIM1
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"activates"| STIM1
    FERROPTOSIS -->|"activates"| STIM1
    STING -->|"activates"| STIM1
    AND["AND"]
    AND -->|"activates"| STIM1
    style STIM1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0