TREM1

Understanding Entity Pages

This page aggregates everything SciDEX knows about TREM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for TREM1 — Triggering Receptor Expressed on Myeloid Cells 1

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graph TD
    TREM1["<b>TREM1</b>"]
    neuroinflammation["neuroinflammation"]
    TREM1 -->|"causes"| neuroinflammation
    lipophagy(["lipophagy"])
    TREM1 -->|"inhibits"| lipophagy
    NLRP3["NLRP3"]
    TREM1 -->|"activates"| NLRP3
    cognitive_impairment["cognitive impairment"]
    TREM1 -->|"causes"| cognitive_impairment
    Inflammation{"Inflammation"}
    TREM1 -->|"therapeutic target"| Inflammation
    Diabetes{"Diabetes"}
    TREM1 -->|"activates"| Diabetes
    Aging{"Aging"}
    TREM1 -->|"activates"| Aging
    Neuroinflammation{"Neuroinflammation"}
    TREM1 -->|"therapeutic target"| Neuroinflammation
    Inflammasome(["Inflammasome"])
    TREM1 -->|"activates"| Inflammasome
    Autophagy(["Autophagy"])
    TREM1 -->|"activates"| Autophagy
    INFLAMMATION["INFLAMMATION"]
    TREM1 -->|"therapeutic target"| INFLAMMATION
    LIPOPHAGY["LIPOPHAGY"]
    TREM1 -->|"activates"| LIPOPHAGY
    LP17["LP17"]
    LP17 -->|"inhibits"| TREM1
    lipid_droplets["lipid droplets"]
    lipid_droplets -->|"contributes to"| TREM1
    lipid_droplets -->|"associated with"| TREM1
    lipid_droplets -->|"causes"| TREM1
    NLRP3 -->|"activates"| TREM1
    AGING["AGING"]
    AGING -->|"activates"| TREM1
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| TREM1
    style TREM1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0